A new definition of addiction and its treatment

Substance Use Disorder is a complex illness where compulsive drug use continues despite harmful consequences. What may have once brought relief now feels like a need, not a choice. Addiction isn’t just a brain disease—it stems from the interplay of biological, psychological, social, spiritual, and experiential factors.

Biologically, it alters the brain and body, affecting behavior and thought. Psychologically, shame and mental health symptoms trap individuals in the cycle. Socially, it’s shaped by isolation and judgment. Spiritually, it disrupts meaning and connection. Experientially, trauma and grief often deepen its grip.

The BPSSEM model offers a holistic, flexible framework for understanding these interconnected domains providing tailored care that restores connection, purpose, and hope, guiding each person toward lasting recovery. It pays particular attention to how shame plays a role in all five of the domains.

Overview of BPSSEM

5 Domains

Understanding addiction involves recognizing it as a complex, multifaceted disease—not simply a choice or moral failing. Effective treatment integrates five key domains to provide holistic, personalized support.

Comparison to Other Models

The BPSSEM embraces most of the other models of addiction while rejecting any moral judgement associated with the disease. It integrates the complex interplay of biological, psychological, social, cultural, environmental, and even spiritual factors in the development of addiction. This holistic approach views addiction as neither solely a brain disorder nor merely a matter of personal choice, but rather as a multifaceted phenomenon shaped by neurobiology, life experiences—including trauma—learned behaviors, environmental influences, and deeply held beliefs. By weaving together the insights of neurobiological, biopsychosocial, trauma-informed, behavioral, sociocultural, and spiritual perspectives, the integrative BPSSEM model addresses the nuanced realities of addiction, offering a flexible and compassionate framework through which prevention, treatment, and recovery can be tailored to the unique needs and strengths of each individual.


Addiction Models Approach BPSSEM Difference
Neurobiological Brain disorder; addiction hijacks reward and motivation circuits Addiction is more than a brain disease, emphasizing all aspects of the human experience
Biopsychosocial Interplay between biology, psychology, and social factors Incorporates all features of this model with the addition of the spiritual and experiential domains
Trauma-Informed Addiction as a coping mechanism for unresolved trauma, including ACEs Integrates the power of trauma with the other 5 domains
Behavioral/Cognitive Learned behaviors and thought patterns; reinforcement cycles Honors the importance of cognition but emphasizes how the limbic storm can override choice
Developmental Model
Early onset of use shapes brain development, coping mechanisms, and risk behaviors Recognizes that early onset makes addiction more likely and more difficult to treat
Sociocultural/Environmental Influence of environment, culture, and systemic factors Recognizes the importance of stigma as cultural shame playing a role in all the other domains
12-Step Model Connection to a “Higher Power”; spiritual principles Embraces the role of spirituality in recovery while expanding the model to a more clinically based approach
Moral Model Addiction viewed as a choice or moral failing Rejects this model as a danger bias and misunderstanding of addiction

Real Voices. Real Impact.

Jeff introduced an integrated method for treating addiction, incorporating spirituality in recovery through the Spiritual Platform™. His approach provided clinical spirituality beyond religion and was well-received by staff and patients, who requested his return for future discussions on addiction. Thank you for the great presentations.
— Derek Gwaltney, Chief Marketing Officer Sabino Recovery, Cypress Lake Recovery & Origins Texas Recovery